Saturday, August 22, 2009

Types of mesothelioma

  • Malignant Pleural Mesothelioma
  • Pleural Mesothelioma Symptoms
  • Malignant Mesothelioma
  • Benign Mesothelioma
  • Peritoneal Mesothelioma
  • Pericardial Mesothelioma

Malignant Pleural Mesothelioma:

Malignant Pleural mesothelioma is a cancer of the cells that make up the pleura or lining around the outside of the lungs and inside of the ribs. It is the most common type of mesothelioma and traditional treatments include surgery, chemotherapy and combined approaches utilizing multiple types of therapy (multimodality). Malignant pleural mesothelioma (MPM) affects over 3,000 people a year in the US, and considering the 30- to 40-year latency period between exposure and expression of the disease, there will be an estimated 300,000 cases before the year 2030. Epidemiological studies predict that approximately 250,000 Europeans will develop mesothelioma in the next few decades.

Pleural Mesothelioma Symptoms:
In the early stages of the disease, symptoms are subtle. In the asymptomatic patient, a small buildup of fluid between the lining of the lung and the chest cavity, called a pleural effusion, may be present. Cough and shortness of breath are the most frequent early complaints. Fatigue, weakness and weight loss typically occur later. Pain is also common later in the disease as the tumor invades the chest wall and/or mediastinum (the area in the chest behind the breast bone and in between the two lungs where the heart, major blood vessels, lymph glands, and nerve tissue exist). This type of the disease starts in the chest cavity and can then spread to other parts of the body. Pleural mesothelioma sufferers may also begin to display severe breathing difficulty, weight loss and fever as well as trouble swallowing and even swelling of the face and neck. Some patients may also develop a rasping voice and start coughing up blood. However, there are patients that may not have any significant symptoms at all.

Malignant Mesothelioma:

Tumors of the mesothelium can be benign (noncancerous) or malignant (cancerous). A malignant tumor of the mesothelium is called a malignant mesothelioma. Because most mesothelial tumors are cancerous, malignant mesothelioma is often simply called mesothelioma

Benign Mesothelioma:
A type of tumor that used to be called benign fibrous mesothelioma can form in the pleura surrounding the lungs. The tumor actually starts from tissue under the mesothelium, called the submesothelium. The new name of this tumor is solitary fibrous tumor of the pleura. This disease is usually not cancerous, but cancerous forms can occur. These tumors do not invade adjacent tissues, and the lack of invasion into adjacent tissues is the key microscopic feature that distinguishes these tumors from those labeled malignant. These
tumors are not associated with asbestos exposure and are found with equal frequency in men and women. A similar disease starting in the peritoneum is called solitary fibrous tumor of peritoneum. Complete surgical resection is the treatment of choice.

Peritoneal Mesothelioma:
Malignant peritoneal mesothelioma is a cancer of the cells lining the abdominal cavity. Peritoneal mesothelioma represents about one fifth to one third of all forms of mesothelioma and is a rapidly fatal malignancy with a median survival of less than 1 year. A small percentage of patients have a history of asbestos exposure, sometimes called chrysotile peritoneal mesothelioma, but a search for other cancer-causing agents continues. Traditional treatments include surgery, chemotherapy and combined approaches utilizing multiple types of therapy (multimodality).

Pericardial Mesothelioma:
Pericardial mesothelioma is the rarest form of mesothelioma, accounting for less than 1% of all cases. It is a cancer of the cells that line the heart called the pericardium.

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